Week 6 College Football Odds: Tide is again a big road favorite

Below are this week’s point spreads for Week 6. Once again, the Tide is a huge favorite, -25.5 on the road against the Aggies. The oddsmakers don’t see a very competitive game from the Ags, who are playing with a much worse defense than last season and a freshman quarterback -- against the nation’s No. 4 offense and No. 1 defense. Alabama has covered the last four straight against A&M. The largest spread has been 13 points, meanwhile the Tide have won by 3, 59, 18 and 18 points. Tough game.

There are a couple of interesting ones in here though: I like Michigan’s defense to cover -12 at home against Sparty. Penn State has not played well on the road, but I suspect the Lions get a two-touchdown cover in Evanston. USC is at home and licking their wounds; this team needs style points and is going to cover 34 against the hapless Beavers, one of the worst teams you’ll see all year. Look for Boise to whack BYU on the road (-7). I like BC at home to at least garner a push at +17 against the Hokies. Memphis rebounds with a solid thrashing of UConn. And Maryland covers +30 in the Horseshoe.

SEC teams are in bold, with two teams on a bye -- Arkansas and Mississippi State. Bonus action is below the spreads.

Top 25

Alabama at Texas A&M (+25.5)

Wake Forest at Clemson (-21.5)

Iowa State at Oklahoma (-26.5)

Penn State at Northwestern (+14)

Georgia at Vanderbilt (+14)

Cal at Washington (-27)

Michigan State at Michigan (-12)

West Virginia at TCU (-12)

Wisconsin at Nebraska (+13.5)

Maryland at Ohio State (-30)

Miami at Florida State (PK)

Washington State at Oregon (OFF)

Mississippi at Auburn (-20)

Oregon State at USC (-34)

Virginia Tech at Boston College (+17)

Louisville at NC State (+1)

San Diego State at UNLV (+10)

Stanford at Utah (+4.5)

Notre Dame at North Carolina (+16.5)

LSU at Florida (-4.5)

UCF at Cincinnati (+14)

Week 6 Odds

Arkansas State at Georgia Southern (OFF)

Louisville at NC State (+1)

Memphis at UConn (+14)

Boise State at BYU (+7)

Charleston Southern at Indianan (OFF)

Illinois at Iowa (-18)

Notre Dame at North Carolina (+16.5)

Western Michigan at Buffalo (+10.5)

Eastern Michigan at Toledo (-13)

Central Michigan at Ohio (-10.5)

Ball State at Akron (-9)

Bowling Green at Miami Ohio (-14)

Marshall at Charlotte (+15)

Central Florida at Cincinnati (+14)

Georgia State at Coastal Carolina (+2.5)

Penn State at Northwestern (+14)

Temple at East Carolina (+4.5)

Duke at Virginia (+2.5)

Pittsburgh at Syracuse (-3.5)

Virginia Tech at Boston College (+17)

New Mexico State at Appalachian State (-10)

Maryland at Ohio State (-30)

Wake Forest at Clemson (-21.5)

Minnesota at Purdue (-3.5)

Michigan State at Michigan (-12)

Southern Miss at UTSA (-9)

Western Kentucky at UTEP (+18.5)

Stanford at Utah (+4.5)

UL Lafayette at Idaho (-3.5)

Colorado State at Utah State (+7)

Tulsa at Tulane (-3)

Army at Rice (+12)

San Diego State at UNLV (+10)

Air Force at Navy (-10)

Arkansas at South Carolina (+2)

Arizona at Colorado (-6.5)

Texas Tech at Kansas (+17)

Cal at Washington (-27)

Washington State at Oregon (OFF)

Florida International at Middle Tennessee State (OFF)

Oregon State at USC (-34)

UL Monroe at Texas State (+6.5)

Georgia at Vanderbilt (+14)

West Virginia at TCU (-12)

Louisiana Tech at UAB (+12)

Kent at Northern Illinois (-23)

Florida Atlantic at Old Dominion (+1.5)

LSU at Florida (-4.5)

Iowa State at Oklahoma (-26.5)

SMU at Houston (-8.5)

Missouri at Kentucky (-14)

Wisconsin at Nebraska (+13.5)

Mississippi at Auburn (-20)

Kansas State at Texas (-5.5)

Alabama at Texas A&M (+25.5)

Fresno State at San Jose State (+14.5)

Hawaii at Nevada (+3.5)

Miami at Florida State (PK)

Early Sharp Action:

- Louisville, -1 to -2.5- Miami, PK to -3

- Georgia, -14 to -15.5- Florida, -4.5 to -6

- Ohio State, -30 to -32- Michigan, -12 to -14

- Stanford, -4.5 to -6.5- UCF, -14 to -16

- Virginia, +2.5 to PK- Buffalo, +10.5 to +7.5

- Ohio, -10.5 to -12- Idaho, -3.5 to -5.5

- UNLV, +10 to +8.5- SMU, +8.5 to +5

Notes:

- Florida is favored over LSU for the first time since 2012

- Iowa State is 1-44-1 against Oklahoma since 1961. The Cyclones have lost to OU by double digits in 11 consecutive games.

- Duke is a road favorite for the first time since 11/28/15.